{"id":5280,"date":"2026-05-21T09:50:33","date_gmt":"2026-05-21T13:50:33","guid":{"rendered":"https:\/\/conscience.ca\/?post_type=event&p=5280"},"modified":"2026-05-21T09:51:48","modified_gmt":"2026-05-21T13:51:48","slug":"beacon-presente-lecons-tirees-du-premier-webinaire-du-defi-dream-target-2035-del-ml","status":"publish","type":"event","link":"https:\/\/conscience.ca\/fr\/event\/beacon-presente-lecons-tirees-du-premier-webinaire-du-defi-dream-target-2035-del-ml\/","title":{"rendered":"BEACON pr\u00e9sente : Le\u00e7ons tir\u00e9es du premier webinaire du d\u00e9fi DREAM Target 2035 DEL-ML"},"content":{"rendered":"\n
\"\"<\/figure>\n\n\n\n

Le criblage de biblioth\u00e8ques cod\u00e9es par l’ADN associ\u00e9 \u00e0 l’apprentissage automatique (DEL-ML) constitue une approche prometteuse pour l’identification de mol\u00e9cules candidates au d\u00e9but du processus de d\u00e9couverte de m\u00e9dicaments, mais le domaine cherche encore \u00e0 d\u00e9terminer quelles strat\u00e9gies en mati\u00e8re de repr\u00e9sentation des donn\u00e9es, d’architecture des mod\u00e8les et de s\u00e9lection des mol\u00e9cules candidates donnent r\u00e9ellement des r\u00e9sultats.<\/p>\n\n\n\n

Le premier d\u00e9fi DREAM Target 2035 DEL-ML<\/a> a \u00e9t\u00e9 con\u00e7u pour explorer pr\u00e9cis\u00e9ment cette question. Des \u00e9quipes d\u2019experts en IA et en chimie computationnelle ont travaill\u00e9 \u00e0 l\u2019identification de compos\u00e9s prometteurs pour la prot\u00e9ine cible WDR91, \u00e0 la fois de mani\u00e8re r\u00e9trospective et prospective, en d\u00e9ployant un large \u00e9ventail d\u2019approches computationnelles. Les r\u00e9sultats offrent des enseignements utiles : le choix des donn\u00e9es d\u2019entra\u00eenement s\u2019est r\u00e9v\u00e9l\u00e9 \u00eatre le facteur de diff\u00e9renciation le plus marquant entre les \u00e9quipes, tandis que l\u2019architecture des mod\u00e8les et la repr\u00e9sentation des donn\u00e9es ont eu moins d\u2019impact que ce \u00e0 quoi on aurait pu s\u2019attendre. De nouveaux ligands de WDR91 ont \u00e9galement \u00e9t\u00e9 d\u00e9couverts au cours du processus.<\/p>\n\n\n\n

Ce webinaire pr\u00e9sentera un aper\u00e7u du d\u00e9fi et de ses r\u00e9sultats, suivi des pr\u00e9sentations des \u00e9quipes les plus performantes. L’inscription est gratuite mais obligatoire.<\/p>\n\n\n\n

Pr\u00e9sident : <\/strong>Matthieu Shapira, Structural Genomics Consortium<\/p>\n\n\n\n

Intervenants :<\/strong>
Luca Chiesa, Structural Genomics Consortium
Lei Zhang, New York University Shanghai
Yifan Jiang, The Hospital for Sick Children (Toronto) & Vector Institute
Anna Khapeliukha, Chemspace LLC
Jeff Messer, GSK
Wim Dehaen, University of Chemistry and Technology Prague<\/p>\n\n\n\n

Inscrivez-vous ici<\/em><\/a> pour recevoir le lien Zoom avant l’\u00e9v\u00e9nement.<\/em><\/em><\/p>\n","protected":false},"featured_media":4958,"template":"","event-type":[41],"class_list":["post-5280","event","type-event","status-publish","has-post-thumbnail","hentry","event-type-event-fr-2"],"acf":[],"yoast_head":"\nBEACON pr\u00e9sente : Le\u00e7ons tir\u00e9es du premier webinaire du d\u00e9fi DREAM Target 2035 DEL-ML - Conscience<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/conscience.ca\/fr\/event\/beacon-presente-lecons-tirees-du-premier-webinaire-du-defi-dream-target-2035-del-ml\/\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"BEACON pr\u00e9sente : Le\u00e7ons tir\u00e9es du premier webinaire du d\u00e9fi DREAM Target 2035 DEL-ML - Conscience\" \/>\n<meta property=\"og:description\" content=\"Le criblage de biblioth\u00e8ques cod\u00e9es par l’ADN associ\u00e9 \u00e0 l’apprentissage automatique (DEL-ML) constitue une approche prometteuse pour l’identification de mol\u00e9cules candidates au d\u00e9but du processus de d\u00e9couverte de m\u00e9dicaments, mais le domaine cherche encore \u00e0 d\u00e9terminer quelles strat\u00e9gies en mati\u00e8re de repr\u00e9sentation des donn\u00e9es, d’architecture des mod\u00e8les et de s\u00e9lection des mol\u00e9cules candidates donnent r\u00e9ellement […]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/conscience.ca\/fr\/event\/beacon-presente-lecons-tirees-du-premier-webinaire-du-defi-dream-target-2035-del-ml\/\" \/>\n<meta property=\"og:site_name\" content=\"Conscience\" \/>\n<meta property=\"article:modified_time\" content=\"2026-05-21T13:51:48+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/conscience.ca\/wp-content\/uploads\/2026\/02\/BEACON_website.png\" \/>\n\t<meta property=\"og:image:width\" content=\"1014\" \/>\n\t<meta property=\"og:image:height\" content=\"556\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/png\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Dur\u00e9e de lecture estim\u00e9e\" \/>\n\t<meta name=\"twitter:data1\" content=\"2 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/conscience.ca\\\/fr\\\/event\\\/beacon-presente-lecons-tirees-du-premier-webinaire-du-defi-dream-target-2035-del-ml\\\/\",\"url\":\"https:\\\/\\\/conscience.ca\\\/fr\\\/event\\\/beacon-presente-lecons-tirees-du-premier-webinaire-du-defi-dream-target-2035-del-ml\\\/\",\"name\":\"BEACON pr\u00e9sente : Le\u00e7ons tir\u00e9es du premier webinaire du d\u00e9fi DREAM Target 2035 DEL-ML - 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