{"id":3074,"date":"2024-10-09T11:56:14","date_gmt":"2024-10-09T15:56:14","guid":{"rendered":"https:\/\/conscience.ca\/news\/the-2024-nobel-prizes-in-chemistry-and-physics-recognize-advances-in-fields-crucial-to-drug-discovery\/"},"modified":"2024-10-22T16:01:18","modified_gmt":"2024-10-22T20:01:18","slug":"the-2024-nobel-prizes-in-chemistry-and-physics-recognize-advances-in-fields-crucial-to-drug-discovery","status":"publish","type":"post","link":"https:\/\/conscience.ca\/fr\/news\/the-2024-nobel-prizes-in-chemistry-and-physics-recognize-advances-in-fields-crucial-to-drug-discovery\/","title":{"rendered":"Les prix Nobel de chimie et de physique 2024 r\u00e9compensent les avanc\u00e9es dans des domaines cruciaux pour la d\u00e9couverte de m\u00e9dicaments"},"content":{"rendered":"\n

L’Acad\u00e9mie royale des sciences de Su\u00e8de a annonc\u00e9 mercredi les prix Nobel 2024, dont deux repr\u00e9sentent des avanc\u00e9es significatives dans des domaines scientifiques cruciaux pour la d\u00e9couverte de m\u00e9dicaments et la mission de Conscience. Ces d\u00e9couvertes, qui se sont appuy\u00e9es sur des donn\u00e9es ouvertes de haute qualit\u00e9, illustrent l’importance \u00e0 la fois de la qualit\u00e9 et de l’ouverture des donn\u00e9es pour l’avenir de l’IA dans le d\u00e9veloppement de m\u00e9dicaments.<\/p>\n\n\n\n

Le prix Nobel de chimie<\/a> a \u00e9t\u00e9 attribu\u00e9 conjointement \u00e0 David Baker (Universit\u00e9 de Washington) et \u00e0 Demis Hassabis et John Jumper (Google DeepMind) pour leurs travaux pionniers dans le domaine de la conception informatique des prot\u00e9ines et de la pr\u00e9diction de leur structure, qui transforment notre capacit\u00e9 \u00e0 d\u00e9velopper de nouveaux m\u00e9dicaments. Le prix de physique<\/a> d\u00e9cern\u00e9 \u00e0 Geoffrey Hinton pour ses travaux sur les r\u00e9seaux neuronaux artificiels sous-tend les mod\u00e8les d’IA \u00e0 l’origine de bon nombre de ces d\u00e9couvertes, marquant ainsi une avanc\u00e9e majeure pour l’int\u00e9gration de l’IA dans le domaine de la d\u00e9couverte de m\u00e9dicaments.<\/p>\n\n\n\n

De telles avanc\u00e9es sont essentielles \u00e0 la mission de Conscience qui consiste \u00e0 acc\u00e9l\u00e9rer la d\u00e9couverte de m\u00e9dicaments gr\u00e2ce \u00e0 l’innovation et \u00e0 la collaboration. L’IA jouera sans aucun doute un r\u00f4le dans l’avenir de la d\u00e9couverte de m\u00e9dicaments – nous pensons que la meilleure fa\u00e7on d’avancer est de partager des donn\u00e9es sur lesquelles tout le monde peut travailler, de cr\u00e9er des r\u00e9f\u00e9rences dont tout le monde peut s’inspirer et d’encourager une culture de science ouverte et de collaboration pour construire un domaine de l’IA qui profite \u00e0 tout le monde et ne laisse personne de c\u00f4t\u00e9.<\/p>\n\n\n\n

David Baker a dirig\u00e9 le premier groupe de recherche \u00e0 concevoir de nouvelles prot\u00e9ines \u00e0 partir d’acides amin\u00e9s, qui peuvent \u00eatre utilis\u00e9es comme m\u00e9dicaments, vaccins et nanomat\u00e9riaux. M. Baker collabore depuis longtemps avec nos partenaires du Consortium de g\u00e9nomique structurelle (CGS) \u00e0 Toronto, avec lesquels il a publi\u00e9 de nombreux articles. Les contributions de Demis Hassabis et de John Jumper, par l’interm\u00e9diaire d’AlphaFold, ont r\u00e9volutionn\u00e9 la pr\u00e9diction de la structure des prot\u00e9ines, une \u00e9tape essentielle pour comprendre les m\u00e9canismes des maladies et d\u00e9couvrir de nouveaux m\u00e9dicaments. Ces technologies nous aident \u00e0 pr\u00e9dire comment les prot\u00e9ines se replient et interagissent avec les m\u00e9dicaments, ce qui est essentiel pour mettre au point des traitements efficaces. Des innovations comme celles-ci aident Conscience \u00e0 atteindre son objectif, qui est de rem\u00e9dier aux d\u00e9faillances du march\u00e9 dans le d\u00e9veloppement de m\u00e9dicaments en tirant parti de la science ouverte et collaborative.<\/p>\n\n\n\n

Les travaux de Geoffrey Hinton sur les r\u00e9seaux neuronaux sont \u00e0 la base des mod\u00e8les pilot\u00e9s par l’IA dans la d\u00e9couverte computationnelle de m\u00e9dicaments. La capacit\u00e9 de l’IA \u00e0 passer au crible de vastes ensembles de donn\u00e9es et \u00e0 pr\u00e9dire les r\u00e9sultats est d\u00e9j\u00e0 en train de remodeler l’industrie pharmaceutique, et les d\u00e9fis CACHE de Conscience s’appuient sur ces technologies pour tenter de cr\u00e9er des voies plus efficaces d’identification des m\u00e9dicaments candidats prometteurs gr\u00e2ce \u00e0 l’\u00e9talonnage, \u00e0 la collaboration et au partage des donn\u00e9es.<\/p>\n\n\n\n

Ces perc\u00e9es r\u00e9compens\u00e9es par le prix Nobel sont la preuve de ce que l’IA et les donn\u00e9es ouvertes peuvent accomplir pour l’avenir de la m\u00e9decine lorsque la collaboration est au c\u0153ur de tout cela.<\/p>\n","protected":false},"excerpt":{"rendered":"

L’Acad\u00e9mie royale des sciences de Su\u00e8de a annonc\u00e9 mercredi les prix Nobel 2024, dont deux repr\u00e9sentent des avanc\u00e9es significatives dans des domaines scientifiques cruciaux pour la d\u00e9couverte de m\u00e9dicaments et la mission de Conscience. Ces d\u00e9couvertes, qui se sont appuy\u00e9es sur des donn\u00e9es ouvertes de haute qualit\u00e9, illustrent l’importance \u00e0 la fois de la qualit\u00e9 […]<\/p>\n","protected":false},"author":5,"featured_media":3072,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":""},"categories":[45],"tags":[],"class_list":["post-3074","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-blogue"],"acf":[],"yoast_head":"\nLes prix Nobel de chimie et de physique 2024 r\u00e9compensent les avanc\u00e9es dans des domaines cruciaux pour la d\u00e9couverte de m\u00e9dicaments - Conscience<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/conscience.ca\/fr\/news\/the-2024-nobel-prizes-in-chemistry-and-physics-recognize-advances-in-fields-crucial-to-drug-discovery\/\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Les prix Nobel de chimie et de physique 2024 r\u00e9compensent les avanc\u00e9es dans des domaines cruciaux pour la d\u00e9couverte de m\u00e9dicaments - Conscience\" \/>\n<meta property=\"og:description\" content=\"L’Acad\u00e9mie royale des sciences de Su\u00e8de a annonc\u00e9 mercredi les prix Nobel 2024, dont deux repr\u00e9sentent des avanc\u00e9es significatives dans des domaines scientifiques cruciaux pour la d\u00e9couverte de m\u00e9dicaments et la mission de Conscience. 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