CACHE Challenge #4 identifies a novel ‘hit’ for a cancer immunotherapy target 

In our fourth CACHE Challenge, researchers from across the globe used computational methods to predict molecules to bind CBLB, a cancer immunotherapy target. The top-performing team identified a molecule that was not only bioactive but also chemically novel—an especially significant achievement given the existing patent coverage around this target and the difficulty pharmaceutical companies have […]

Peng Fu Appointed CEO of Conscience

We’re excited to announce that Peng Fu has joined Conscience as our new Chief Executive Officer. He brings deep experience in biotech, finance, and law, and we’re looking forward to seeing how his leadership can help us move closer to our vision: a future where no patient is left behind. For more information, contact:Estrid Jakobsen […]

Expansion of the CACHE Governing Board

We are proud to announce the expansion of the CACHE Governing Board, which now includes representatives from four pharmaceutical companies; UCB, AstraZeneca, Bayer, and Boehringer Ingelheim. The Governing Board’s role is to actively lead and provide direction for the CACHE challenges, as well as nominate members for its independent expert panels for target selection, application […]

DMOS program funds three projects working towards treatments for rare diseases

We are proud to announce the first three recipients of funding via our Developing Medicines through Open Science program. These grantees are working towards treatments and cures for three rare diseases: a genetic neuromuscular disorder, a pediatric brain cancer, and a liver disease. Access this press release on Business Wire For more information, contact:Estrid Jakobsen […]

CACHE Challenge #2 identifies seven ‘hits’ for pan-coronavirus treatment

coronavirus

In our second CACHE Challenge, researchers from across the globe identified seven promising early-stage molecules that could lead to a new treatment effective against all coronaviruses, advancing preparedness for future pandemic threats. For more information, contact:Estrid Jakobsen at [email protected] Preeti Singh at [email protected] Conscience Announces Top Performers in Open Science Challenge to Design Promising Pan-Coronavirus Drugs […]

CACHE Challenge predicts seven ‘hits’ for Parkinson’s disease

Scientist Working in The Laboratory

Our first open science competition identified seven promising molecules that show potential for new, more effective drugs for familial Parkinson’s disease. For more information, contact: Preeti Singh at [email protected] Conscience Announces First Success in Open Science Challenge to Predict “Hits” for Parkinson’s Disease Drugs Click here to download this release in PDF. Structural Genomics Consortium […]

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